EP2343287A1 — New 2-aminothiadiazole derivatives

USPTO Abstract

The present invention relates to a compound of formula (I), or a pharmaceutically acceptable salt or N-oxide thereof: wherein: €¢ L represents a direct bond or a -S(O) 2 - group, €¢ n is an integer having a value from 0 to 2, €¢ R1 represents a pyridyl group or an imidazo[1,2-a]pyridinyl group, wherein the pyridyl group is substituted with one or more substituents selected from halogen atoms, a hydroxy group, a C 1-4 alkyl group and a C 1-4 alkoxy group, or €¢ R 1 represents a group of formula: wherein: o R a and R b independently represent a hydrogen atom, halogen atom or a linear or branched C 1-4 alkyl group, o R c represents a hydroxy group, a linear or branched C 1-4 alkyl group or C 1-4 alkoxy group wherein the alkyl and the alkoxy groups independently are optionally substituted with one or more substituents selected from hydroxy group, cyano group and-NR'R" groups and wherein –  R' represents a hydrogen atom or a linear or branched C 1-4 alkyl group, –  R" represents a hydrogen atom or a linear or branched C 1-4 alkyl group optionally substituted with a hydroxycarbonyl group; or –  R' and R" together with the nitrogen atom to which they are attached form a 4 to 6 membered, saturated heterocyclic ring optionally substituted with a hydroxycarbonyl group. €¢ R 2 represents a pyridyl group, a C 3-6 cycloalkyl group or a phenyl group which is optionally substituted with one or more substituents selected from halogen atoms, cyano group, and C 1-4 alkoxy group; and €¢ R 3 represents a C 3-6 cycloalkyl group, a C 3-6 cycloalkyl-C 1-2 alkyl group or a linear or branched C 2-4 alkyl group optionally substituted with one or more substituents selected from halogen atoms and C 1-2 alkoxy group.