EP Patent

EP2330892A1 — Methods of treatment using ammonia-scavenging drugs

Assigned to Horizon Therapeutics LLC · Expires 2011-06-15 · 15y expired

What this patent protects

The invention provides a method for determining a dose and schedule and making dose adjustments of PBA prodrugs used to treat nitrogen retention states, or ammonia accumulation disorders, by measuring urinary excretion of phenylacetylglutamine and/or total urinary nitrogen. The i…

USPTO Abstract

The invention provides a method for determining a dose and schedule and making dose adjustments of PBA prodrugs used to treat nitrogen retention states, or ammonia accumulation disorders, by measuring urinary excretion of phenylacetylglutamine and/or total urinary nitrogen. The invention provides methods to select an appropriate dosage of a PBA prodrug based on the patient's dietary protein intake, or based on previous treatments administered to the patient. The methods are applicable to selecting or modifying a dosing regimen for a subject receiving an orally administered ammonia scavenging drug.

Drugs covered by this patent

Patent Metadata

Patent number
EP2330892A1
Jurisdiction
EP
Classification
—
Expires
2011-06-15
Drug substance claim
No
Drug product claim
No
Assignee
Horizon Therapeutics LLC
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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