EP1904067B1 — Pharmaceutical formulation of carboxamide hiv integrase inhibitors containing a release rate controlling composition
Assigned to Merck Sharp and Dohme LLC · Expires 2013-11-20 · 12y expired
What this patent protects
Pharmaceutical formulations suitable for oral administration in solid dosage forms are described. The compositions comprise an effective amount of a base salt of a compound of Formula I and a release rate controlling composition comprising a solubilizing agent, a gelling agent, a…
USPTO Abstract
Pharmaceutical formulations suitable for oral administration in solid dosage forms are described. The compositions comprise an effective amount of a base salt of a compound of Formula I and a release rate controlling composition comprising a solubilizing agent, a gelling agent, and a water soluble filler; wherein Formula I is: wherein R 1 , R 2 , R 3 and R 4 are defined herein. The formulations are suitable for use in the inhibition of HIV integrase, the treatment and prophylaxis of HIV infection, and the treatment, prophylaxis and delay in the onset of AIDS.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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