EP1896075A2 — Pharmaceutical compositions comprising tacrolimus and a cyp3a4 inhibitor
Assigned to Veloxis Pharmaceuticals AS · Expires 2008-03-12 · 18y expired
What this patent protects
A pharmaceutical composition comprising a CYP3A4 inhibitor and tacrolimus or an analogue thereof, wherein the composition upon administration to a human in need thereof results in a relative AUCinvention/AUC separate value of tacrolimus of at least about 1.1 , the AUC values bein…
USPTO Abstract
A pharmaceutical composition comprising a CYP3A4 inhibitor and tacrolimus or an analogue thereof, wherein the composition upon administration to a human in need thereof results in a relative AUCinvention/AUC separate value of tacrolimus of at least about 1.1 , the AUC values being determined under similar conditions and the AUCseparate value is determined after administration of tacrolimus and CYP3A4 inhibitor in separate dosage forms.
Drugs covered by this patent
- Prograf (TACROLIMUS) · Astellas Pharma
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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