EP1800681A1 — SOLID PHARMACEUTICAL COMPOSITION COMPRISING THE THIAZOLYL METHYL ESTER OF [5S-(5R*,8R*,10R*,11R*)]-10-HYDROXY-2-METHYL-5-(1-METHYLETHYL)-1-[2-1(1-METHYLETHYL)-4-THIAZOLYL]-3,6-DIOXO-8,11-BIS(PHENYLMETHYL)-2,4,7,12-TETRAAZATRIDECAN-13-OIC ACID AND PREPARATION METHOD THEREOFvvv
Assigned to Coll Farma Sl · Expires 2007-06-27 · 19y expired
What this patent protects
A solid pharmaceutical composition comprising the triazolyl methyl ester of acid [5S-(5R*,8R*,10R*,11R*)]-10-hydroxi-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic and a compound which enables the pen…
USPTO Abstract
A solid pharmaceutical composition comprising the triazolyl methyl ester of acid [5S-(5R*,8R*,10R*,11R*)]-10-hydroxi-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-2,4,7,12-tetraazatridecan-13-oic and a compound which enables the penetration of the gastrointestinal fluid in said composition, which is selected from among the group comprising silicates and silica oxide, and a process for the manufacturing of said composition, which comprises a kneading step in which the speed and time of addition of the solvent is thoroughly controlled.
Drugs covered by this patent
- Tybost (COBICISTAT) · Gilead Sciences
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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