EP1644536A4 — GENETIC RESPONSE MARKER FOR ATYPICAL ANTIPSYCHOTICS AND ANTIDEPRESSANTS AND METHODS OF USE THEREOF
Assigned to State Of Queensland Acting Through Queensland · Expires 2008-07-23 · 18y expired
What this patent protects
The invention provides methods of identifying candidate psychiatric patients, or patients with movement disorder, for treatment with medication that acts at a D2 dopan-line receptor site or increases density of D2 dopamine receptors. The method comprises determining a patient's D…
USPTO Abstract
The invention provides methods of identifying candidate psychiatric patients, or patients with movement disorder, for treatment with medication that acts at a D2 dopan-line receptor site or increases density of D2 dopamine receptors. The method comprises determining a patient's DRD2 genotype. Patients having the Taq1A (A1) allele (A1 + allelic status) are candidates for treatment with high dose, high binding antipsychotics and/or SSRIs that influence D2 receptor density. Patients lacking the Taq1A allele (A1- allelic status) are candidates for treatment with low dose, low binding atypical antipsychotics, and are not likely to respond well to these SSRIs.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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