EP Patent

EP1495769B1 — Mannose-6-phosphate receptor mediated gene transfer into muscle cells

Assigned to LBR Medbiotech BV · Expires 2008-02-27 · 18y expired

What this patent protects

The invention relates to glycoside-compound conjugates for use in antisense strategies, particularly in vivo antisense strategies. The conjugates comprise a glycoside linked to a compound, in which glycoside is a ligand capable of binding to a mannose-6-phosphate receptor of a mu…

USPTO Abstract

The invention relates to glycoside-compound conjugates for use in antisense strategies, particularly in vivo antisense strategies. The conjugates comprise a glycoside linked to a compound, in which glycoside is a ligand capable of binding to a mannose-6-phosphate receptor of a muscle cell. For example the cells are muscle cells of a Duchenne Muscular Dystrophy (DMD) patient and the conjugate comprises an antisense oligonucleotide which causes exon skipping and induces or restores the synthesis of dystrophin or variants thereof. <IMAGE>

Drugs covered by this patent

Patent Metadata

Patent number
EP1495769B1
Jurisdiction
EP
Classification
—
Expires
2008-02-27
Drug substance claim
No
Drug product claim
No
Assignee
LBR Medbiotech BV
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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