EP Patent

EP1495769A1 — Mannose-6-phosphate receptor mediated gene transfer into muscle cells

Assigned to LBR Medbiotech BV · Expires 2005-01-12 · 21y expired

What this patent protects

The invention relates to glycoside-compound conjugates for use in antisense strategies, particularly in vivo antisense strategies. The conjugates comprise a glycoside linked to a compound, in which glycoside is a ligand capable of binding to a mannose-6-phosphate receptor of a mu…

USPTO Abstract

The invention relates to glycoside-compound conjugates for use in antisense strategies, particularly in vivo antisense strategies. The conjugates comprise a glycoside linked to a compound, in which glycoside is a ligand capable of binding to a mannose-6-phosphate receptor of a muscle cell. For example the cells are muscle cells of a Duchenne Muscular Dystrophy (DMD) patient and the conjugate comprises an antisense oligonucleotide which causes exon skipping and induces or restores the synthesis of dystrophin or variants thereof.

Drugs covered by this patent

Patent Metadata

Patent number
EP1495769A1
Jurisdiction
EP
Classification
—
Expires
2005-01-12
Drug substance claim
No
Drug product claim
No
Assignee
LBR Medbiotech BV
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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