EP1176141A4 — HETEROCYCLIC COMPOUNDS HAVING RECEPTOR ACTIVATION EFFECT $ g (a) 4 $ g (b) 2 OF NICOTINIC ACETYLCHOLINE

USPTO Abstract

Heterocyclic compounds showing an affinity for nicotinic acetylcholine α4β2 receptor and activating the same to thereby exert a preventive or therapeutic effect on brain diseases. Namely, nicotinic acetlycholine α4β2 receptor activators comprising, as the active ingredient, compounds represented by general formula (I) or pharmacologically acceptable salts thereof and drugs containing the same: wherein A represents optionally substituted aryl or an optionally subsituted heterocycle; X represents oxygen, sulfur, carbon or nitrogen; dotted lines represent each the presence or absence of a bond; n is an integer of 1 or 2; and Y represents alkylene, etc.