EP1062240B1 — N-terminally modified glp-1 derivatives
Assigned to Novo Nordisk AS · Expires 2010-04-28 · 16y expired
What this patent protects
The present invention relates to N-terminally modified derivatives of human glucagon-like peptide-1 (GLP-1) and analogues thereof having a protracted profile of action, as well as the use of such derivatives in pharmaceutical compositions for the treatment of obesity, insulin dep…
USPTO Abstract
The present invention relates to N-terminally modified derivatives of human glucagon-like peptide-1 (GLP-1) and analogues thereof having a protracted profile of action, as well as the use of such derivatives in pharmaceutical compositions for the treatment of obesity, insulin dependent or non-insulin dependent diabetes mellitus. The GLP-1 derivatives have a lipophilic substituent attached to at least one amino acid residue and are substituted at the N-terminal end with a substituent comprising an optionally substituted 5- or 6-membered ring system, e.g. an imidazole.
Drugs covered by this patent
- Ozempic (semaglutide) · Novo Nordisk
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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