EP1054004A1 — Novel pyrimidine-5-carboxamide derivatives

USPTO Abstract

Pyrimidine-5-carboxamide derivatives represented by a general formula (I) or salts thereof [wherein each symbol has the following meaning; X: O, S, NR 1 , CO, NR 1 CO, CONR 1 , C=N-OR 1 or a bond, Y: a lower alkylene group which may be substituted by OR 1 or -NHR 1 , or a bond, Z: O, NR 2 or a bond, A: H, or a lower alkyl which may have a substituent, a -CO-lower alkyl which may have a substituent, an aryl which may have a substituent, a heteroaryl which may have a substituent, a cycloalkyl which may have a substituent or a nitrogen-containing saturated heterocyclic group which may have a substituent, B: an aryl which may have a substituent or a heteroaryl group which may have a substituent, R 1 , R 2 : H, a lower alkyl or a -CO-lower alkyl group].