EP0982300A2 — Non-imidazole alkylamines as histamine H3 - receptor ligands and their therapeutic applications

USPTO Abstract

Compounds of formula (A): <CHEM> wherein: W is a residue which imparts antagonistic and/or agonistic activity at histamine H3-receptors when attached to an imidazole ring in 4(5) position. R<1> and R<2> may be identical or different and represent each independently a lower alkyl or cycloalkyl, or taken together with the nitrogen atom to which they are attached, a saturated nitrogen-containing ring (i) as defined, a non-aromatic unsaturated nitrogen-containing ring (ii) as defined, a morpholino group, or a N-substituted piperazino group as defined. Compounds (A) are useful for preparing medicaments acting as antagonists and/or agonists at the H3-receptors of histamine.