EP Patent

EP0812186B1 — Method for loading lipid vesicles

Assigned to University of British Columbia · Expires 2001-10-31 · 25y expired

What this patent protects

Methods for the preparation of stable liposome formulations of protonatable therapeutic agents. The methods involve loading a therapeutic agent into preformed liposomes having a methylamine concentration gradient across the lipid bilayer of the liposomes. These methods provide li…

USPTO Abstract

Methods for the preparation of stable liposome formulations of protonatable therapeutic agents. The methods involve loading a therapeutic agent into preformed liposomes having a methylamine concentration gradient across the lipid bilayer of the liposomes. These methods provide liposome formulations which are more stable, more cost effective, and easier to prepare in a clinical environment than those previously available. The present invention also provides the pharmaceutical compositions prepared by the above methods, a kit for the preparation of liposome formulations of therapeutic agents, and methods for their use.

Drugs covered by this patent

Patent Metadata

Patent number
EP0812186B1
Jurisdiction
EP
Classification
—
Expires
2001-10-31
Drug substance claim
No
Drug product claim
No
Assignee
University of British Columbia
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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