EP0810195A1 — Process for manufacturing 1-(3-trifluoromethyl)phenyl-propan-2-one intermediate in the synthesis of the fenfluramine
Assigned to Alfa Chemicals Italiana SpA · Expires 1997-12-03 · 28y expired
What this patent protects
Process for manufacturing 1-(3-trifluoromethyl)phenyl-propan-2-one intermediate in the synthesis of the anorexic drug fenfluramine . The process comprises reacting the diazonium salt of the 3-trifluoromethylaniline with isopropenyl acetate in a polar solvent in presence of catal…
USPTO Abstract
Process for manufacturing 1-(3-trifluoromethyl)phenyl-propan-2-one intermediate in the synthesis of the anorexic drug fenfluramine . The process comprises reacting the diazonium salt of the 3-trifluoromethylaniline with isopropenyl acetate in a polar solvent in presence of catalytic amounts of a cuprous or cupric salt or of a mixture thereof and, optionally, of a base and purifying the raw product through bisulfite complex or distillation under vacuum.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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