EP0788493A1 — Taxoid derivatives, their preparation and their use as antitumor agents
Assigned to Research Foundation of the State University of New York · Expires 1997-08-13 · 29y expired
What this patent protects
This invention relates to a taxoid of formula (I), wherein R1 is a C¿3?-C5 alkyl or alkenyl radical; R?2¿ is a C¿3?-C5 branched alkyl radical; R?3 and R4¿ are independently selected from hydrogen and hydroxyl protecting groups including functional groups which increase the water …
USPTO Abstract
This invention relates to a taxoid of formula (I), wherein R1 is a C¿3?-C5 alkyl or alkenyl radical; R?2¿ is a C¿3?-C5 branched alkyl radical; R?3 and R4¿ are independently selected from hydrogen and hydroxyl protecting groups including functional groups which increase the water solubility of the taxoid antitumor agent; R5 is a hydrogen, an acyl radical, or an alkoxylcarbonyl or carbamoyl radical; and R6 is an acyl radical. The compounds of formula (I) are useful as antitumor agents or their precursors. This invention also relates to a pharmaceutical composition having antineoplastic activity comprising the compound of formula (I) and a physiologically acceptable carrier and method of treatment using the compound of formula (I).
Drugs covered by this patent
- Vumerity (DIROXIMEL FUMARATE) · Biogen
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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