EP Patent

EP0788481A1 — Process for preparing levobupivacaine and analogues thereof

Assigned to Darwin Discovery Ltd · Expires 1997-08-13 · 29y expired

What this patent protects

PCT No. PCT/GB95/02514 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Oct. 23, 1995 PCT Pub. No. WO96/12700 PCT Pub. Date May 2, 1996A process for preparing levobupivacaine, racemic bupivacaine or another N-alkyl analogue thereof, comprises chlorinating pipe…

USPTO Abstract

PCT No. PCT/GB95/02514 Sec. 371 Date Apr. 25, 1997 Sec. 102(e) Date Apr. 25, 1997 PCT Filed Oct. 23, 1995 PCT Pub. No. WO96/12700 PCT Pub. Date May 2, 1996A process for preparing levobupivacaine, racemic bupivacaine or another N-alkyl analogue thereof, comprises chlorinating pipecolic acid hydrochloride, amidation of the resultant pipecolyl chloride hydrochloride in solvent, without isolation, with 2,6-dimethylaniline, and alkylation of the resultant pipecolic acid 2,6-xylidide. Alternatively, the alkylation may be followed by the amidation.

Drugs covered by this patent

Patent Metadata

Patent number
EP0788481A1
Jurisdiction
EP
Classification
—
Expires
1997-08-13
Drug substance claim
No
Drug product claim
No
Assignee
Darwin Discovery Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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