EP0767656B1 — Lipid based composition containing diacylglycerol, phospholipid, polar liquid and biologically active material

USPTO Abstract

PCT No. PCT/SE95/00593 Sec. 371 Date Nov. 27, 1996 Sec. 102(e) Date Nov. 27, 1996 PCT Filed May 24, 1995 PCT Pub. No. WO95/34287 PCT Pub. Date Dec. 21, 1995A biologically active composition containing (a) a diacyl glycerol, (b) a phospholipid and, optionally, (c) a polar liquid in such proportions that they together form an L2-phase or a cubic liquid crystalline phase, in which a biologically active material is dissolved or dispersed. A method for preparing the composition by mixing (a), (b) and, optionally, (c) for forming an L2-phase or a cubic liquid crystalline phase, the biologically active material being added before, during or after the formation of said phase. Use of the L2-phase or the cubic liquid crystalline phase for encapsulating a biologically active material for obtaining a preparation is provided, which yields a controlled release of the biologically active material.