EP Patent

EP0747390A2 — Reducing gelation of a fatty acid acylated protein using a citrate buffer

Assigned to Eli Lilly and Co · Expires 1996-12-11 · 29y expired

What this patent protects

A method for processing a fatty acid-acylated protein, especially N-palmitoyl Lys B29 human insulin, to reduce the incidence of gelation by conducting such processing in the presence of a citrate buffering agent as the primary buffer which method allows such processing to be con…

USPTO Abstract

A method for processing a fatty acid-acylated protein, especially N-palmitoyl Lys B29 human insulin, to reduce the incidence of gelation by conducting such processing in the presence of a citrate buffering agent as the primary buffer which method allows such processing to be conducted at higher protein concentrations and with less temperature control than would otherwise be possible in the absence of the citrate buffer.

Drugs covered by this patent

Patent Metadata

Patent number
EP0747390A2
Jurisdiction
EP
Classification
—
Expires
1996-12-11
Drug substance claim
No
Drug product claim
No
Assignee
Eli Lilly and Co
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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