EP0680960A1 — Imidazole compound

USPTO Abstract

The invention aims at providing a novel compound having vitamin H₃ receptor antagonism and relates to a compound represented by general formula (O) or pharmaceutically acceptable salts thereof, wherein m represents an integer of 4 to 6; R₁ represents hydrogen, lower alkyl or aralkyl; R₂ and R₃ may be the same or different from each other and each represents hydrogen or lower alkyl; R₄ represents hydrogen, linear or branched alkyl, cycloalkyl, cycloalkylalkyl, optionally substituted aryl, or optionally substituted aralkyl; Z represents R₅ or A-R₆; A represents S or O; R₅ represents hydrogen, lower alkyl, optionally substituted aryl, or optionally substituted aralkyl; and R₆ represents lower alkyl, lower alkenyl, lower alkynyl, or optionally substituted aralkyl.