EP0607607A1 — Xanthine derivatives

USPTO Abstract

Disclosed are xanthine derivatives represented by the following Formula (I): in which R¹, R², and R³ independently represent hydrogen or lower alkyl; Q¹, Q², and Q³ independently represent hydrogen, lower alkyl, lower alkoxy, or halogen; and X represents -COR⁴ (in which R⁴ represents hydrogen, hydroxy, lower alkyl, or lower alkoxy) or -SO₂R⁵ {in which R⁵ represents hydroxy, lower alkoxy, trifluoromethyl, in which R⁶ and R⁷ independently represent hydrogen, hydroxy-substituted or unsubstituted lower alkyl, aryl, or (in which m represents an integer of 1 to 3; and R⁸ and R⁹ independently represent hydrogen or lower alkyl), or (in which Y represents a single bond, oxygen, or N-R¹⁰ in which R¹⁰ represents hydrogen or lower alkyl; and n1 and n2 independently represent an integer of 1 to 3 )}, and pharmaceutically acceptable salts thereof.