EP Patent

EP0592446B1 — Loading technique for preparing drug containing liposomes

Assigned to Nexstar Pharmaceuticals Inc · Expires 1995-10-04 · 31y expired

What this patent protects

A process for loading of cationic, anionic or ionizable drugs through lipid bilayer membranes in the absence of a pH gradient comprises the formation of liposomes in an aqueous medium containing a combination of either the salt of an anion with high membrane permeability and a ca…

USPTO Abstract

A process for loading of cationic, anionic or ionizable drugs through lipid bilayer membranes in the absence of a pH gradient comprises the formation of liposomes in an aqueous medium containing a combination of either the salt of an anion with high membrane permeability and a cation with low membrane permeability if the compound to be entrapped is an anionic drug or has an anionic potential; or the salt of a cation with high membrane permeability and an anion with low membrane permeability if the compound to be entrapped is a cationic drug or has a cationic potential.

Drugs covered by this patent

Patent Metadata

Patent number
EP0592446B1
Jurisdiction
EP
Classification
—
Expires
1995-10-04
Drug substance claim
No
Drug product claim
No
Assignee
Nexstar Pharmaceuticals Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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