EP0556889A1 — Method of preparing aryl(homo)piperazines
Assigned to Duphar International Research BV · Expires 1993-08-25 · 33y expired
What this patent protects
The present invention is concerned with a method for the preparation of a compound of the general formula 2 by reaction of a compound of the formula 3 Ar-Y (3) with a compound of the general formula 4 wherein Ar means a (hetero)aryl grou…
USPTO Abstract
The present invention is concerned with a method for the preparation of a compound of the general formula 2 by reaction of a compound of the formula 3 Ar-Y (3) with a compound of the general formula 4 wherein Ar means a (hetero)aryl group, preferably selected from phenyl, naphtyl, furyl, thienyl, pyridyl, bicylic heteroaryl and tricyclic heteroaryl, which (hetero)aryl group is optionally sustituted with one to five non-strongly-electron-withdrawing substituents; M is a metal from the groups I or II of the periodic table; R₁₂ is an electronegative group; and n is 0 or 1. The invention also relates to compounds prepared according to this method and to new substituted aryl(homo)piperazines.
Drugs covered by this patent
- Velsipity (Etrasimod Arginine) · Pfizer Inc.
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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