EP Patent

EP0407122A1 — Novel modified PF4 compositions and methods of use

Assigned to Repligen Corp · Expires 1991-01-09 · 35y expired

What this patent protects

The subject invention pertains to the use of modified PF4 and recombinant PF4 (rPF4) as well as modified analogs (mutants) of PF4, and peptide fragments thereof, to inhibit angiogenesis. The modified PF4, analogs, and certain fragments are shown to have utility for treating angio…

USPTO Abstract

The subject invention pertains to the use of modified PF4 and recombinant PF4 (rPF4) as well as modified analogs (mutants) of PF4, and peptide fragments thereof, to inhibit angiogenesis. The modified PF4, analogs, and certain fragments are shown to have utility for treating angiogenic diseases and for the inhibition of endothelial cell proliferation. Also, the subject invention concerns modifications of PF4 which facilitate the targeting of the biological activity of PF4 to specific locations.

Drugs covered by this patent

Patent Metadata

Patent number
EP0407122A1
Jurisdiction
EP
Classification
—
Expires
1991-01-09
Drug substance claim
No
Drug product claim
No
Assignee
Repligen Corp
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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