EP Patent

EP0382220A2 — Method for preparing aminothiazolylacetic acid derivatives

Assigned to Meiji Seika Kaisha Ltd · Expires 1990-08-16 · 36y expired

What this patent protects

Aminothiazolylacetic acid derivatives of formula (I) are new. wherein R¹ is an easily cleavable amino-protective group, R⁴ and R⁵ are different from each other and each is a hydrogen or methyl group, R⁶ is a carboxylic acid-­protective group, and A is hydrogen, an alkali me…

USPTO Abstract

Aminothiazolylacetic acid derivatives of formula (I) are new. wherein R¹ is an easily cleavable amino-protective group, R⁴ and R⁵ are different from each other and each is a hydrogen or methyl group, R⁶ is a carboxylic acid-­protective group, and A is hydrogen, an alkali metal or a quaternary ammonium salt. The compounds are useful as the substituent on the 7-position of antibacterial cephalosporin derivatives. The compounds are obtained by reacting a new compound of formula (II) and a palladium salt or palladium compound in the presence of a triphenylphosphine or trialkyl phosphite and an alkali metal alkanoate or organic base.

Drugs covered by this patent

Patent Metadata

Patent number
EP0382220A2
Jurisdiction
EP
Classification
—
Expires
1990-08-16
Drug substance claim
No
Drug product claim
No
Assignee
Meiji Seika Kaisha Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.