EP0371731A2 — Quinazolinone derivatives
Assigned to Smith Kline and French Laboratories Ltd · Expires 1990-06-06 · 36y expired
What this patent protects
Compounds of the formula (1) : and pharmaceutically acceptable salts thereof are described wherein R¹ is C₁₋₆alkyl, C₂₋₆alkenyl, C₃₋₅cycloalkylC₁₋₄alkyl, phenylC₁₋₄alkyl or C₁₋₄alkyl substituted by 1 to 6 fluoro groups; R² is hydrogen, C₁₋₆alkyl, C₁₋₆alkylthio, C₁₋₆alkoxy…
USPTO Abstract
Compounds of the formula (1) : and pharmaceutically acceptable salts thereof are described wherein R¹ is C₁₋₆alkyl, C₂₋₆alkenyl, C₃₋₅cycloalkylC₁₋₄alkyl, phenylC₁₋₄alkyl or C₁₋₄alkyl substituted by 1 to 6 fluoro groups; R² is hydrogen, C₁₋₆alkyl, C₁₋₆alkylthio, C₁₋₆alkoxy, nitro or -NR³R⁴; and R³ and R⁴ are independently hydrogen or C₁₋₄alkyl optionally substituted by hydroxy provided that the carbon atom adjacent to the nitrogen atom is not substituted by hydroxy; with the proviso that R¹ is not methyl or ethyl when R² is hydrogen. Processes for their preparation, pharmaceutical compositions containing them and their use as medicaments are described.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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