EP0354638A2 — Use of adenosine and its derivatives in diagnosis

USPTO Abstract

The invention comprises the use, in the preparation of a diagnostic agent for parenteral administration to humans, of adenosine a functional adenosine receptor agonist including 1-­methyl-2-phenylethyl adenosine, 5-ethyl carboxamide adenosine, cyclopentyl adenosine and 2-chloro adenosine; a metabolic precursor or by-product of adenosine including adenine and inosine; or a phosphorylated derivative of adenosine including adenosine monophosphate, adenosine diphosphate and adenosine triphosphate. The diagnostic agent is used in detecting the presence, or assessing the severity, of vascular disease.