EP Patent

EP0334551A1 — Anti-neoplastic formulations

Assigned to Abic Ltd · Expires 1989-09-27 · 37y expired

What this patent protects

Carboplatin is conventionally made into extemporaneous injectable solutions by reconstituting a lyophilisate with water or a dextrose or saline solution. This is difficult and dangerous, and the solutions formed are unstable. The invention provides a stable, ready-made, inj…

USPTO Abstract

Carboplatin is conventionally made into extemporaneous injectable solutions by reconstituting a lyophilisate with water or a dextrose or saline solution. This is difficult and dangerous, and the solutions formed are unstable. The invention provides a stable, ready-made, injectable aqueous carboplatin solution made without reconstituting a lyophilisate - thus, from unlyophilised carboplatin. The solution preferably contains from 10 mg/ml to 15 mg/ml carboplatin, advantageously includes a polyol (up to 10% of mannitol), and a preservative, but is salt-free, and has a pH preferably between 5 and 7.

Drugs covered by this patent

Patent Metadata

Patent number
EP0334551A1
Jurisdiction
EP
Classification
—
Expires
1989-09-27
Drug substance claim
No
Drug product claim
No
Assignee
Abic Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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