EP0324938A1 — Concentrated stabilized microbubble-type ultrasonic imaging agent and method of production
Assigned to GE Healthcare AS · Expires 1989-07-26 · 37y expired
What this patent protects
A microbubble-type ultrasonic imaging agent is provided comprising a parenterally-administerable aqueous medium containing a dispersion of microspheres predominantly of diameters less than 10 microns, wherein the microspheres consist of gas microbubbles encapsulated with water-…
USPTO Abstract
A microbubble-type ultrasonic imaging agent is provided comprising a parenterally-administerable aqueous medium containing a dispersion of microspheres predominantly of diameters less than 10 microns, wherein the microspheres consist of gas microbubbles encapsulated with water-insolubilized biocompatible material. The imaging agent is characterized by having a concentration of greater than 100 x 10⁶ microspheres per milliliter, and a stability such that this concentration is maintained for over 4 weeks at a temperature of 20 to 25°C. A preferred method of producing the imaging agent is also disclosed.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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