EP0281200A1 — Pharmaceutical composition, pharmaceutical granulate and process for their preparation
Assigned to Astellas Pharma Europe BV · Expires 1988-09-07 · 38y expired
What this patent protects
A pharmaceutical tablet is provided containing an amphoteric beta-lactam antibiotic, a cellulose product, being microcrystalline cellulose or microfine cellulose or a mixture of both, and a second disintegrant, being low-substituted hydroxypropylcellulose, which fully disintegrat…
USPTO Abstract
A pharmaceutical tablet is provided containing an amphoteric beta-lactam antibiotic, a cellulose product, being microcrystalline cellulose or microfine cellulose or a mixture of both, and a second disintegrant, being low-substituted hydroxypropylcellulose, which fully disintegrates in water within 60 seconds. When swallowed it shows a bioavailability as good as a pharmacy prepared suspension of the antibiotic. The tablet is compressed from a mixture containing a new granulate which is prepared from the antibiotic substance, microcrystalline cellulose and/or microfine cellulose and water only. Such tablets can also be prepared by using other known tablet disintegrants as the second disintegrant.
Drugs covered by this patent
- Prilosec (omeprazole) · AstraZeneca (originally Astra AB)
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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