EP0264904A2 — Pharmaceutical compositions containing benzoyl urea derivatives

USPTO Abstract

A pharmaceutical composition comprising a benzoyl urea compound (A) selected from the group consisting of a benzoyl urea compound (I) having the formula: wherein X is a halogen atom, a nitro group or a trifluoromethyl group, provided that when Y is a nitro group, X is a halogen atom or a nitro group, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, Z₁ is a halogen atom or a trifluoromethyl group, Z₂ is a hydrogen atom or a halogen atom, and A is a =CH- group or a nitrogen atom, and a benzoyl urea compound (II) having the formula: wherein each of X₁ and X₂ is a hydrogen atom, a halogen atom or a nitro group, provided that when Y is a nitro group, X₁ is a hydrogen atom, Y is a hydrogen atom, a halogen atom, a nitro group or a trifluoromethyl group, and Z is a hydrogen atom, a halogen atom or a trifluoromethyl group, as an active ingredient; a nonionic surfactant as a dispersant; and at least one member selected from the group consisting of a saccharide, a saccharide alcohol, silicic anhydride and a nonionic surfactant, as a disintegrator.