EP0232569A1 — 1-Benzyl-2-(N-substituted)-carbamoyl-tetrahydroisoquinolines and method for the preparation thereof
Assigned to Pharmachim TPO · Expires 1987-08-19 · 39y expired
What this patent protects
1-benzyl-2-(N-substituted)-carbamoyl-tetrahydroisoquinolines of the following formula: <CHEM> in which R1 and R2 are independently hydroxyl or methoxyl groups, R3 is hydrogen or a methoxyl group and R4 is a methyl or chloroethyl group have an inhibiting effect on beta-ade…
USPTO Abstract
1-benzyl-2-(N-substituted)-carbamoyl-tetrahydroisoquinolines of the following formula: <CHEM> in which R1 and R2 are independently hydroxyl or methoxyl groups, R3 is hydrogen or a methoxyl group and R4 is a methyl or chloroethyl group have an inhibiting effect on beta-adenylatecyclase. The compounds are prepared by reaction of the corresponding 2-unsubstituted tetrahydroisoquinoline with an isocyanate of formula R4-N=C=O.
Drugs covered by this patent
- Xalatan (LATANOPROST) · Thea Pharma
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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