EP0124068A1 — New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same
Assigned to Lehner AG · Expires 1984-11-07 · 42y expired
What this patent protects
New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic bile acids having in the side chain in the 17 position a cyclopropane ring are described together with taurine and glycine conjugated derivatives thereof. The compounds of the invention, prepared fr…
USPTO Abstract
New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic bile acids having in the side chain in the 17 position a cyclopropane ring are described together with taurine and glycine conjugated derivatives thereof. The compounds of the invention, prepared from suitable olephinic intermediates by reaction with alkyl diazoacetates or by Simmons-Smith reaction and optional conjugation with taurine or glycine, are endowed with interesting therapeutic properties.
Drugs covered by this patent
- Ocaliva (OBETICHOLIC ACID) · Intercept Pharms Inc
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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