EP0021178B1 — Maytansinoids, their production and use
Assigned to Takeda Pharmaceutical Co Ltd · Expires 1984-01-18 · 42y expired
What this patent protects
Novel maytansinoids of the formula: <IMAGE> wherein Y is H or Cl, and R is C2-15alkyl, phenyl-C1-4alkyl, pyridyl-C1-4alkyl, imidazolyl-C1-4alkyl, indolyl-C1-4alkyl, furyl-C1-4alkyl or thienyl-C1-4alkyl, said R group being substituted by hydroxyl, halogen or C1-5alkanoylox…
USPTO Abstract
Novel maytansinoids of the formula: <IMAGE> wherein Y is H or Cl, and R is C2-15alkyl, phenyl-C1-4alkyl, pyridyl-C1-4alkyl, imidazolyl-C1-4alkyl, indolyl-C1-4alkyl, furyl-C1-4alkyl or thienyl-C1-4alkyl, said R group being substituted by hydroxyl, halogen or C1-5alkanoyloxy at its alpha - and/or beta -position, have antimitotic, antitumor and antimicrobial activities.
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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