EP Patent

EP0000716A2 — Pyrrolo(2,1-b)(3)benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them

Assigned to Merck and Co Inc · Expires 1979-02-21 · 47y expired

What this patent protects

Compounds of formula: wherein X and Y are hydrogen, halogen, trifluoromethyl, alkyl, alkoxy, cyano, trifluoromethylthio, or trifluoromethylsulfonyl; and R is alkyl or cyclopropylmethyl, and the dotted line represents saturation or unsaturation, have utility as antipsychotic …

USPTO Abstract

Compounds of formula: wherein X and Y are hydrogen, halogen, trifluoromethyl, alkyl, alkoxy, cyano, trifluoromethylthio, or trifluoromethylsulfonyl; and R is alkyl or cyclopropylmethyl, and the dotted line represents saturation or unsaturation, have utility as antipsychotic agents. They also demonstrate antiserotonin and antihistaminic activity. They are prepared by reaction of a pyrrolo (2,1-b) (3) benzazepin-11-one with a piperidinyl magnesium halide followed by dehydration

Drugs covered by this patent

Patent Metadata

Patent number
EP0000716A2
Jurisdiction
EP
Classification
—
Expires
1979-02-21
Drug substance claim
No
Drug product claim
No
Assignee
Merck and Co Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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