CN Patent

CN1340500A — 三或四取代苯基化合物、其制备方法及应用

Assigned to Individual · Expires 2002-03-20 · 24y expired

What this patent protects

本发明公开了一种作为PDEIV抑制剂的三或四取代苯基化合物、其制备方法及其在医药学方面的应用;对烷基或烷氧基苯甲酸经酯化、硝化,得到的3－硝基－4－烷基或烷氧基取代苯甲酸酯与二卤代苯胺或胺基取代二卤代杂环化合物反应,得到酰胺类化合物,将其中的硝基还原为胺基,再将胺基重氮化、水解,得到的N—二卤代苯胺或杂环取代－3－羟基－4－烷基或烷氧基取代苯甲酰胺在碱催化下与卤代烷反应,得到题述化合物。

USPTO Abstract

本发明公开了一种作为PDEIV抑制剂的三或四取代苯基化合物、其制备方法及其在医药学方面的应用;对烷基或烷氧基苯甲酸经酯化、硝化,得到的3－硝基－4－烷基或烷氧基取代苯甲酸酯与二卤代苯胺或胺基取代二卤代杂环化合物反应,得到酰胺类化合物,将其中的硝基还原为胺基,再将胺基重氮化、水解,得到的N—二卤代苯胺或杂环取代－3－羟基－4－烷基或烷氧基取代苯甲酰胺在碱催化下与卤代烷反应,得到题述化合物。

Drugs covered by this patent

Patent Metadata

Patent number: CN1340500A
Jurisdiction: CN
Classification: —
Expires: 2002-03-20
Drug substance claim: No
Drug product claim: No
Assignee: Individual
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.