CN Patent

CN119638675A — 一种嘧啶苯胺类化合物的晶型、制备方法及应用

Assigned to Zhengzhou Tongyuankang Pharmaceutical Co ltd · Expires 2025-03-18 · 1y expired

What this patent protects

本发明涉及一种嘧啶苯胺类化合物的酸式盐的多晶型、制备方法及应用。具体地，本发明公开了如式(A)化合物的酸式盐的多晶型和其制备方法，以及所述的多晶型的应用。综合热力学稳定性关系和固态性质评估的结果，本发明提供如式(A)的枸橼酸盐晶型Ⅰ为优选晶型，理化性质稳定，可更好地用于临床。

USPTO Abstract

本发明涉及一种嘧啶苯胺类化合物的酸式盐的多晶型、制备方法及应用。具体地，本发明公开了如式(A)化合物的酸式盐的多晶型和其制备方法，以及所述的多晶型的应用。综合热力学稳定性关系和固态性质评估的结果，本发明提供如式(A)的枸橼酸盐晶型Ⅰ为优选晶型，理化性质稳定，可更好地用于临床。

Drugs covered by this patent

Patent Metadata

Patent number
CN119638675A
Jurisdiction
CN
Classification
—
Expires
2025-03-18
Drug substance claim
No
Drug product claim
No
Assignee
Zhengzhou Tongyuankang Pharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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