CN Patent

CN119528821B — 一种阿普昔腾坦的制备方法

Assigned to ZHEJIANG GUOBANG PHARMACEUTICAL CO Ltd · Expires 2025-10-10 · 1y expired

What this patent protects

本申请提供一种阿普昔腾坦的制备方法，属于杂环化合物技术领域。以马昔腾坦为原料，马昔腾坦溶解在C1~C4的单取代低级醇中，在固体酸作用下于50~110℃水解得到中间体Ⅱ，中间体Ⅱ与氨基磺酰氯反应得到阿普昔腾坦。本申请用于阿普昔腾坦的制备，具有反应路线短、合成简单、转化率较高、便于进行工业化的放大等优点。

USPTO Abstract

本申请提供一种阿普昔腾坦的制备方法，属于杂环化合物技术领域。以马昔腾坦为原料，马昔腾坦溶解在C1~C4的单取代低级醇中，在固体酸作用下于50~110℃水解得到中间体Ⅱ，中间体Ⅱ与氨基磺酰氯反应得到阿普昔腾坦。本申请用于阿普昔腾坦的制备，具有反应路线短、合成简单、转化率较高、便于进行工业化的放大等优点。

Drugs covered by this patent

Patent Metadata

Patent number
CN119528821B
Jurisdiction
CN
Classification
—
Expires
2025-10-10
Drug substance claim
No
Drug product claim
No
Assignee
ZHEJIANG GUOBANG PHARMACEUTICAL CO Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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