CN Patent

CN119306698B — 一种制备扎维吉泮中间体的新方法

Assigned to Zhejiang University of Technology ZJUT · Expires 2025-10-21 · 1y expired

What this patent protects

本发明公开了一种制备扎维吉泮中间体的新方法，该中间体为3‑(哌啶‑4‑基)‑1,2‑二氢喹啉‑2‑酮盐酸盐，该中间体制备方法为：以哌啶‑4‑乙酸衍生物和苯胺为起始原料，依次经缩合反应、环化反应、水解反应制得3‑(哌啶‑4‑基)‑1,2‑二氢喹啉‑2‑酮盐酸盐。本发明的制备方法步骤简短，原料廉价易得，成本较低，避免深冷反应，对设备要求低，产物收率和纯度较高，适合工业化生产。

USPTO Abstract

本发明公开了一种制备扎维吉泮中间体的新方法，该中间体为3‑(哌啶‑4‑基)‑1,2‑二氢喹啉‑2‑酮盐酸盐，该中间体制备方法为：以哌啶‑4‑乙酸衍生物和苯胺为起始原料，依次经缩合反应、环化反应、水解反应制得3‑(哌啶‑4‑基)‑1,2‑二氢喹啉‑2‑酮盐酸盐。本发明的制备方法步骤简短，原料廉价易得，成本较低，避免深冷反应，对设备要求低，产物收率和纯度较高，适合工业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN119306698B
Jurisdiction
CN
Classification
—
Expires
2025-10-21
Drug substance claim
No
Drug product claim
No
Assignee
Zhejiang University of Technology ZJUT
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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