CN119176856B — Pegcetacoplan的制备方法
Assigned to Hangzhou Nuotanuohe Biopharmaceutical Technology Co ltd · Expires 2025-03-18 · 1y expired
What this patent protects
本发明涉及药物合成技术领域,尤其是涉及一种Pegcetacoplan的制备方法。Pegcetacoplan的制备方法,包括如下步骤:Pegcetacoplan中间体环肽与PEG衍生物于溶剂中,在碱的作用下进行偶联反应,得到所述Pegcetacoplan。本发明将Pegcetacoplan中间体环肽与特定PEG衍生物进行偶联反应,并对该体系下的偶联反应条件进行探究,既提高了偶联效率,又减少了副反应,提高收率,更适于大规模的生产。
USPTO Abstract
本发明涉及药物合成技术领域,尤其是涉及一种Pegcetacoplan的制备方法。Pegcetacoplan的制备方法,包括如下步骤:Pegcetacoplan中间体环肽与PEG衍生物于溶剂中,在碱的作用下进行偶联反应,得到所述Pegcetacoplan。本发明将Pegcetacoplan中间体环肽与特定PEG衍生物进行偶联反应,并对该体系下的偶联反应条件进行探究,既提高了偶联效率,又减少了副反应,提高收率,更适于大规模的生产。
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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