CN Patent

CN118772124A — 一种Suzetrigine的制备方法

Assigned to Shandong Fuchang Pharmaceutical Co ltd · Expires 2024-10-15 · 2y expired

What this patent protects

本发明公开了一种Suzetrigine的制备方法，反应路线如下反应式1所示。该方法采用4‑氨基吡啶‑2‑甲酰胺与化合物1的羧基直接发生缩合反应，一步法制备最终的产品Suzetrigine。相对于已有工艺，步骤更短、反应更安全，避免了酸做成酰氯可能的消旋风险，以及氨甲醇溶液的使用和排放，反应条件更加适合于绿色工业化生产。

USPTO Abstract

本发明公开了一种Suzetrigine的制备方法，反应路线如下反应式1所示。该方法采用4‑氨基吡啶‑2‑甲酰胺与化合物1的羧基直接发生缩合反应，一步法制备最终的产品Suzetrigine。相对于已有工艺，步骤更短、反应更安全，避免了酸做成酰氯可能的消旋风险，以及氨甲醇溶液的使用和排放，反应条件更加适合于绿色工业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN118772124A
Jurisdiction
CN
Classification
—
Expires
2024-10-15
Drug substance claim
No
Drug product claim
No
Assignee
Shandong Fuchang Pharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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