CN Patent

CN118063533B — 修饰的核苷酸化合物、其寡聚核苷酸及其应用

Assigned to Guangzhou Bebet Pharmaceutical Co ltd · Expires 2024-08-27 · 2y expired

What this patent protects

本发明公开了一种具有式(I)所示结构的修饰核苷酸化合物或者其药学上可接受的盐或者其立体异构体，其寡聚核苷酸及其应用。将本发明提供的修饰的核苷酸化合物连接到寡核苷酸的5'‑末端，可以提升寡核苷酸抑制基因表达的活性，并且可以提高寡聚核苷酸在体内的稳定性，从而有效提高其在体内的成药性。

USPTO Abstract

本发明公开了一种具有式(I)所示结构的修饰核苷酸化合物或者其药学上可接受的盐或者其立体异构体，其寡聚核苷酸及其应用。将本发明提供的修饰的核苷酸化合物连接到寡核苷酸的5'‑末端，可以提升寡核苷酸抑制基因表达的活性，并且可以提高寡聚核苷酸在体内的稳定性，从而有效提高其在体内的成药性。

Drugs covered by this patent

Patent Metadata

Patent number
CN118063533B
Jurisdiction
CN
Classification
—
Expires
2024-08-27
Drug substance claim
No
Drug product claim
No
Assignee
Guangzhou Bebet Pharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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