CN Patent

CN117487866A — 一种合成γ-叔醇-(S)-α-氨基酸的酶催化方法

Assigned to Shanghai Institute of Materia Medica of CAS · Expires 2024-02-02 · 2y expired

What this patent protects

本发明公开了一种合成γ‑叔醇‑(S)‑α‑氨基酸的酶催化方法，包括：在磷酸吡哆醛存在下，UstD酶催化L‑天冬氨酸脱羧并和邻位二酮类化合物发生羰基加成反应，生成手性γ‑叔醇‑(S)‑α‑氨基酸。该方法操作简单、反应条件温和、立体选择性和区域选择性好，转化率高。

USPTO Abstract

本发明公开了一种合成γ‑叔醇‑(S)‑α‑氨基酸的酶催化方法，包括：在磷酸吡哆醛存在下，UstD酶催化L‑天冬氨酸脱羧并和邻位二酮类化合物发生羰基加成反应，生成手性γ‑叔醇‑(S)‑α‑氨基酸。该方法操作简单、反应条件温和、立体选择性和区域选择性好，转化率高。

Drugs covered by this patent

Patent Metadata

Patent number
CN117487866A
Jurisdiction
CN
Classification
—
Expires
2024-02-02
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Institute of Materia Medica of CAS
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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