CN Patent
CN117466866B — Hedgehog信号通路抑制剂
Assigned to Beijing Tiantan Hospital · Expires 2026-03-24 · 0y expired
What this patent protects
本发明涉及一种新型Hedgehog信号通路抑制剂及其制备方法,所述Hedgehog信号通路抑制剂具有式(I)所示结构。本发明的Hedgehog信号通路抑制剂能有效地抑制SMO受体活性,阻滞SHH信号通路。具有良好的阻滞由大脑中过度或超同步的神经元放电所引起的癫痫发作的作用。作为癫痫治疗候选药物具有良好应用前景。
USPTO Abstract
本发明涉及一种新型Hedgehog信号通路抑制剂及其制备方法,所述Hedgehog信号通路抑制剂具有式(I)所示结构。本发明的Hedgehog信号通路抑制剂能有效地抑制SMO受体活性,阻滞SHH信号通路。具有良好的阻滞由大脑中过度或超同步的神经元放电所引起的癫痫发作的作用。作为癫痫治疗候选药物具有良好应用前景。
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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