CN Patent

CN117337168A — 向中枢神经系统的核酸递送

Assigned to Bojian Massachusetts Co ltd · Expires 2024-01-02 · 2y expired

What this patent protects

本发明提供具有经封装核酸(例如反义寡核苷酸)的聚合物纳米载体(例如PLGA纳米粒子)，用于递送(例如鞘内)至中枢神经系统。这些聚合纳米载体可用于治疗中枢神经系统病症。与游离或未配制的反义寡核苷酸相比，其能够以更高量在更长时间段内递送其货物(例如反义寡核苷酸)且将所述货物递送至更深的脑部区域。反义寡核苷酸的有效递送和分布使得施用次数减少且引起患者依从性且改善患者体验。

USPTO Abstract

本发明提供具有经封装核酸(例如反义寡核苷酸)的聚合物纳米载体(例如PLGA纳米粒子)，用于递送(例如鞘内)至中枢神经系统。这些聚合纳米载体可用于治疗中枢神经系统病症。与游离或未配制的反义寡核苷酸相比，其能够以更高量在更长时间段内递送其货物(例如反义寡核苷酸)且将所述货物递送至更深的脑部区域。反义寡核苷酸的有效递送和分布使得施用次数减少且引起患者依从性且改善患者体验。

Drugs covered by this patent

Patent Metadata

Patent number
CN117337168A
Jurisdiction
CN
Classification
—
Expires
2024-01-02
Drug substance claim
No
Drug product claim
No
Assignee
Bojian Massachusetts Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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