CN Patent

CN117285533B — CD47/SIRPα小分子抑制剂及其应用和抗肿瘤药物组合物

Assigned to Sichuan Academy Of Medical Sciences Sichuan Provincial People's Hospital · Expires 2024-01-30 · 2y expired

What this patent protects

本发明涉及CD47/SIRPα小分子抑制剂及其应用和抗肿瘤药物组合物，属于抗肿瘤药物技术领域。本发明解决的技术问题是提供一种新型的CD47/SIRPα小分子抑制剂。该CD47/SIRPα小分子抑制剂的结构式为式Ⅰ所示。本发明开发出了一种新型的CD47的小分子化合物，能够作为CD47/SIRPα小分子抑制剂，靶向于CD47‑SIRPα通路，阻断CD47/SIRPα结合，大大激活机体免疫能力，增强肿瘤免疫治疗效果，为研发新型的肿瘤免疫治疗的药物提供思路。

USPTO Abstract

本发明涉及CD47/SIRPα小分子抑制剂及其应用和抗肿瘤药物组合物，属于抗肿瘤药物技术领域。本发明解决的技术问题是提供一种新型的CD47/SIRPα小分子抑制剂。该CD47/SIRPα小分子抑制剂的结构式为式Ⅰ所示。本发明开发出了一种新型的CD47的小分子化合物，能够作为CD47/SIRPα小分子抑制剂，靶向于CD47‑SIRPα通路，阻断CD47/SIRPα结合，大大激活机体免疫能力，增强肿瘤免疫治疗效果，为研发新型的肿瘤免疫治疗的药物提供思路。

Drugs covered by this patent

Patent Metadata

Patent number
CN117285533B
Jurisdiction
CN
Classification
—
Expires
2024-01-30
Drug substance claim
No
Drug product claim
No
Assignee
Sichuan Academy Of Medical Sciences Sichuan Provincial People's Hospital
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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