CN Patent

CN117138047B — Tlr4抑制剂在制备缓解索拉非尼所致胃肠道毒性的药物中的应用

Assigned to Sun Yat Sen University · Expires 2025-12-09 · 0y expired

What this patent protects

本发明公开了TLR4抑制剂在制备缓解索拉非尼所致胃肠道毒性的药物中的应用，涉及生物医药领域。TLR4抑制剂对索拉非尼诱导的胃肠道毒性具有缓解作用，能够回调索拉非尼导致的小鼠体重增加缓慢，缓解索拉非尼导致的小鼠肠黏膜损伤，减轻索拉非尼导致的肠道氧化应激。

USPTO Abstract

本发明公开了TLR4抑制剂在制备缓解索拉非尼所致胃肠道毒性的药物中的应用，涉及生物医药领域。TLR4抑制剂对索拉非尼诱导的胃肠道毒性具有缓解作用，能够回调索拉非尼导致的小鼠体重增加缓慢，缓解索拉非尼导致的小鼠肠黏膜损伤，减轻索拉非尼导致的肠道氧化应激。

Drugs covered by this patent

Patent Metadata

Patent number
CN117138047B
Jurisdiction
CN
Classification
—
Expires
2025-12-09
Drug substance claim
No
Drug product claim
No
Assignee
Sun Yat Sen University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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