CN Patent
CN116942671B — ALK inhibitor 2在制备治疗食管鳞癌的药物中的应用
Assigned to Air Force Medical University · Expires 2024-02-27 · 2y expired
What this patent protects
本发明属于医药领域,具体涉及ALK inhibitor 2在制备治疗食管鳞癌的药物中的应用。本发明的究结果表明,ALK inhibitor 2能够高效抑制RSK4酶的表达,且能够高效的抑制食管鳞癌细胞的增殖、侵袭和迁移,与Afatinib联用,能够显著抑制食管鳞癌埃克替尼耐药株的增殖,该结果为食管鳞癌患者的治疗和预后提供了一种有效的技术手段。
USPTO Abstract
本发明属于医药领域,具体涉及ALK inhibitor 2在制备治疗食管鳞癌的药物中的应用。本发明的究结果表明,ALK inhibitor 2能够高效抑制RSK4酶的表达,且能够高效的抑制食管鳞癌细胞的增殖、侵袭和迁移,与Afatinib联用,能够显著抑制食管鳞癌埃克替尼耐药株的增殖,该结果为食管鳞癌患者的治疗和预后提供了一种有效的技术手段。
Drugs covered by this patent
- Zykadia (ceritinib) · Novartis
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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