CN Patent

CN116789609A — 一种(r)-2-(哌嗪-2-基)乙腈盐酸盐的制备方法

Assigned to Nanjing Youfu Pharmaceutical Technology Co ltd · Expires 2023-09-22 · 3y expired

What this patent protects

本发明属于医药中间体技术领域，具体涉及一种(R)‑2‑(哌嗪‑2‑基)乙腈盐酸盐的制备方法，该(R)‑2‑(哌嗪‑2‑基)乙腈盐酸盐的制备是以(S)‑1‑BOC‑3‑羟甲基哌嗪为起始原料，经过PMBCl保护、EsCl活化、TMSCN氰基化、ACE‑Cl脱PMB共四步反应得到成品。本发明提供的制备方法设计科学合理，制备过程中避免使用危险试剂、剧毒试剂和贵重试剂，能够以较低的成本来实现(R)‑2‑(哌嗪‑2‑基)乙腈盐酸盐的安全制备。

USPTO Abstract

本发明属于医药中间体技术领域，具体涉及一种(R)‑2‑(哌嗪‑2‑基)乙腈盐酸盐的制备方法，该(R)‑2‑(哌嗪‑2‑基)乙腈盐酸盐的制备是以(S)‑1‑BOC‑3‑羟甲基哌嗪为起始原料，经过PMBCl保护、EsCl活化、TMSCN氰基化、ACE‑Cl脱PMB共四步反应得到成品。本发明提供的制备方法设计科学合理，制备过程中避免使用危险试剂、剧毒试剂和贵重试剂，能够以较低的成本来实现(R)‑2‑(哌嗪‑2‑基)乙腈盐酸盐的安全制备。

Drugs covered by this patent

Patent Metadata

Patent number
CN116789609A
Jurisdiction
CN
Classification
—
Expires
2023-09-22
Drug substance claim
No
Drug product claim
No
Assignee
Nanjing Youfu Pharmaceutical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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