CN Patent

CN116694758A — Lsd1基因的用途及相关产品

Assigned to Center for Excellence in Molecular Cell Science of CAS · Expires 2023-09-05 · 3y expired

What this patent protects

本发明属于生物医药研究领域，公开了LSD1基因的用途及相关产品。LSD1基因作为靶标在制备抗肺腺癌恶化和/或抗肺腺癌耐药的药物中的用途。本发明发现LSD1基因缺失，能抑制肺腺癌、腺鳞癌向肺鳞癌的转分化，同时抑制腺鳞癌、肺鳞癌的发生；进一步，通过LSD1抑制剂同样能抑制腺鳞癌、肺腺癌向肺鳞癌的转分化，同时抑制腺鳞癌、肺鳞癌的发生；更进一步，经LSD1抑制剂处理后抑制了肺鳞癌的发生。因此，LSD1基因能作为抗肺腺癌恶化潜在的治疗靶点，同时LSD1基因能作为克服肺腺癌靶向治疗中产生耐药性的潜在的治疗靶点。

USPTO Abstract

本发明属于生物医药研究领域，公开了LSD1基因的用途及相关产品。LSD1基因作为靶标在制备抗肺腺癌恶化和/或抗肺腺癌耐药的药物中的用途。本发明发现LSD1基因缺失，能抑制肺腺癌、腺鳞癌向肺鳞癌的转分化，同时抑制腺鳞癌、肺鳞癌的发生；进一步，通过LSD1抑制剂同样能抑制腺鳞癌、肺腺癌向肺鳞癌的转分化，同时抑制腺鳞癌、肺鳞癌的发生；更进一步，经LSD1抑制剂处理后抑制了肺鳞癌的发生。因此，LSD1基因能作为抗肺腺癌恶化潜在的治疗靶点，同时LSD1基因能作为克服肺腺癌靶向治疗中产生耐药性的潜在的治疗靶点。

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Patent Metadata

Patent number
CN116694758A
Jurisdiction
CN
Classification
—
Expires
2023-09-05
Drug substance claim
No
Drug product claim
No
Assignee
Center for Excellence in Molecular Cell Science of CAS
Source
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Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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