CN Patent

CN116492349B — 奥沙普秦和异烟肼低共熔物、药物组合物及其制备方法

Assigned to Southeast University · Expires 2025-09-09 · 1y expired

What this patent protects

本发明公开了一种奥沙普秦和异烟肼低共熔物、药物组合物及其制备方法，该低共熔混合物通过溶剂辅助研磨法制备得到，包括摩尔比为0.1～0.9的奥沙普秦和异烟肼，奥沙普秦+异烟肼低共熔物在134±4℃熔化。相比单独的奥沙普秦和异烟肼，低共熔混合物的熔点显著下降，而且显著改善了原先水溶性极差的奥沙普秦的溶出速率和溶解度。本发明提供的药物组合物易于工业化生产和应用，具有良好的应用前景。

USPTO Abstract

本发明公开了一种奥沙普秦和异烟肼低共熔物、药物组合物及其制备方法，该低共熔混合物通过溶剂辅助研磨法制备得到，包括摩尔比为0.1～0.9的奥沙普秦和异烟肼，奥沙普秦+异烟肼低共熔物在134±4℃熔化。相比单独的奥沙普秦和异烟肼，低共熔混合物的熔点显著下降，而且显著改善了原先水溶性极差的奥沙普秦的溶出速率和溶解度。本发明提供的药物组合物易于工业化生产和应用，具有良好的应用前景。

Drugs covered by this patent

Patent Metadata

Patent number
CN116492349B
Jurisdiction
CN
Classification
—
Expires
2025-09-09
Drug substance claim
No
Drug product claim
No
Assignee
Southeast University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.